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ea0037ep346 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Association between +276 G>T polymorphism of the adiponectin gene (ADIPOQ) and insulin resistance in Ukrainian patients with type 2 diabetes mellitus (T2DM)

Karachentsev Yuri , Kravchun Nonna , Gorshunska Maryanna , Atramentova Lubov , Krasova Nataliia , Tyzhnenko Tatyana , Leshchenko Zhanna , Gladkih Alexander , Pochernyaev Artyom , Opaleiko Yuliia , Plohotnichenko Olga , Poltorak Victoria

Variants of ADIPOQ have been inconsistently associated with adiponectin level in diverse populations. We explored association of single nucleotide polymorphism (SNP) in the ADIPOQ (+276 G>T, rs1501299) with circulating total adiponectin and insulin resistance (IR) in Ukrainian T2DM cohort.Materials and methods: 544 T2DM patients (M/F: 241/303, age 56.3±0.4 years, diabetes duration 7.8±1.0 years, BMI 31.7&...

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Endocrine Abstracts

Association between +276 G>T polymorphism of the adiponectin gene (ADIPOQ) and insulin resistance in Ukrainian patients with type 2 diabetes mellitus (T2DM)

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